SimAuthor: Harnessing Foundation Models for Persistent Scientific Simulator Authoring

Yishan Wang, Ran Piao, Mathias Funk, Aaqib Saeed (Eindhoven University of Technology)

· 2026
PPGECGcardiac-audiorespiratory-audio

Summary

Treats "scientific simulator authoring" as an LLM program-search problem with weak empirical feedback. A persistent harness revises executable simulator code with PUCT parent selection, a fixed modality evaluator that returns a scalar score plus a structured discrepancy report, a model-written scientific blueprint, and a mechanism library of reusable code changes. Six tasks: VSD and AS (cardiac audio), COPD (respiratory audio), AF in PPG (search set MIMIC PERform AF, 96 windows / 12 subjects; held-out Long-term AF wrist-PPG, Bacevičius 2024, 40 / 8), LQT and WPW (ECG; PTB-XL → Chapman–Shaoxing).

Updated: Oct 6, 2026