Engineering digital biomarkers of interstitial glucose from noninvasive smartwatches
Brinnae Bent, Peter J. Cho, Maria Henriquez, April Wittmann, Connie Thacker, Mark Feinglos, Matthew J. Crowley, Jessilyn P. Dunn
npj Digital Medicine 4:89· 2026
Summary
Empatica E4 wristband + Dexcom G6 CGM, 16 participants, 8–10 days each, >25,000 interstitial glucose readings. E4 streams: PPG 64 Hz (HR at 1 Hz, IBI-based HRV), EDA and skin temperature 4 Hz, accelerometer 32 Hz. Food logs.
Key facts
- Form Factor
- wrist
- License
- Not stated
Updated: Oct 11, 2026
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