FiLMamba: A FiLM-Conditioned Mamba Architecture with an Energy-Efficient FPGA Accelerator for Generalizable Cuffless Blood Pressure Estimation

Fan He, Jinhong Wu, Wenxian Li, Yan Li, Xiaoyang Zeng

IEEE Transactions on Biomedical Circuits a· 2026
PPGDOI

Summary

Addresses PPG morphology–BP ambiguity (similar waveforms → different pressures across subjects → mean regression) with a selective state-space (Mamba) model conditioned via Feature-wise Linear Modulation (FiLM) on a 4-D hemodynamic state vector, plus Cross-Domain Hemodynamic Alignment (CDHA) (unlabeled BN recalibration + per-calibration-unit bias correction). Evaluated on MIMIC-BP (1,524 patients): SBP/DBP SDE 6.45 / 4.96 mmHg, >2.5× better than unconditioned baselines; claims AAMI compliance. Training-free transfer to UCI-BP: 4.29 / 3.24 mmHg SDE — abstract claims first AAMI-compliant training-free cross-dataset cuffless BP result.

Key facts

Form Factor
lab

Reported benchmarks

Cuffless blood pressure

MIMIC-BP · SDE (mmHg) ↓

#1 of 1
6.45 / 4.96

MIMIC-BP SDE SBP/DBP; clinical/lab PPG

Cuffless blood pressure

uci-bp · SDE (mmHg) ↓

#1 of 1
4.29 / 3.24

UCI-BP transfer SDE; clinical/lab

Updated: Oct 1, 2026