Accelerometry-Assessed Latent Class Patterns of Physical Activity and Sedentary Behavior With Mortality
Activity counts measure attention, not model quality. Missing counts are unknown. Publication status follows the linked source; a listed venue alone does not confirm peer review.
Evenson and colleagues applied latent class analysis to one week of hip-worn accelerometry from 4,510 NHANES 2003-2006 participants aged 40 and over, with mortality follow-up through 2011. Over an average of 6.6 years (513 deaths), more-active classes had lower all-cause mortality than the least active class. The class spending the most of the day in sedentary bouts had about twice the mortality risk of the class with the fewest (adjusted HR 2.10, 95% CI 1.11-3.97).
- Signals: Accelerometer
- Result: Cox proportional hazards models provided adjusted hazard ratios with 95% CIs.
- Result: The class with the highest percentage of the day in sedentary bouts (Class 1) had a higher risk of mortality (adjusted hazard ratio, 2.10; 95% CI=1.11, 3.97) versus the class with fewer sedentary bouts (Class 7).
- Venue
- American Journal of Preventive Medicine
- Published
- 2017
- arXiv
- Not reported
- Licence
- Not reported
- Signals
- Not reported
- Form factor
- Not reported
- Devices
- Subjects
- Not reported
- Code
- Not reported
- Added
- Oct 15, 2026
Abstract
IntroductionLatent class analysis provides a method for understanding patterns of physical activity and sedentary behavior. This study explored the association of accelerometer-assessed patterns of physical activity/sedentary behavior with all-cause mortality.MethodsThe sample included 4,510 U.S. National Health and Nutrition Examination Survey participants aged ≥40 years enrolled in 2003-2006 with mortality follow-up through 2011. Participants used a hip-worn accelerometer for 1 week that provided minute-by-minute information on physical activity/sedentary behavior. Accelerometry patterns were derived using latent class analysis. Cox proportional hazards models provided adjusted hazard ratios with 95% CIs. Analyses were conducted from 2014 to 2016.ResultsDuring an average of 6.6 years of follow-up, 513 deaths occurred. For average counts/minute, the more-active classes had a lower risk of mortality compared with the lowest (Class 1). Findings were generally similar for percentage of the day in minutes and bouts of moderate to vigorous physical activity, defined two ways. For percentage of the day in sedentary behavior, generally no associations were identified. However, the class with the highest percentage of the day in sedentary bouts (Class 1) had a higher risk of mortality (adjusted hazard ratio, 2.10; 95% CI=1.11, 3.97) versus the class with fewer sedentary bouts (Class 7).ConclusionsIn this national observational study, time spent in physical activity reduced the risk of all-cause mortality and time spent in sedentary bouts increased the risk of all-cause mortality, regardless of how both were accumulated. The latent class analysis contributed to understanding the impact of patterning of physical activity and sedentary behavior on mortality.
Verbatim fromEurope PMC· Abstract via Europe PMC; © the authors/publisher
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Cite
@article{evensonlcaactivitymortal2017,
title = {{Accelerometry-Assessed Latent Class Patterns of Physical Activity and Sedentary Behavior With Mortality}},
author = {Kelly R. Evenson and Amy H. Herring and Fang Wen},
year = {2017},
journal = {American Journal of Preventive Medicine},
doi = {10.1016/j.amepre.2016.10.033}
}History
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