Mayo LBNP hypovolemia: non-invasive biomarkers during lower body negative pressure

Raw data associated with the study entitled "Non-Invasive Biomarkers for Detecting Progression Toward Hypovolemic Cardiovascular Instability In A Lower Body Negative Pressure Model". There were 16 subjects with 1. electrocardiogram (ECG), 2. mean arterial pressure (MAP), 3) photoplethysmography (pleth), 4) Bioimpedance Cardiography measured via a Cheetah (Startling/Medtronic) system referred to as cheetah, 5) electrical impedance from a Sentec electrical impedance tomography system, referred to as ST, and electrical impedance from a sciospec impedance analyzer, referred to as SS. Each subject underwent a lower body negative pressure (LBNP) procedure, where the LBNP was increased modeling a small hemorrhage by drawing blood to their lower extremeties. The dataset contains 5 mat (MATLAB data files), with time reported in minutes on the day of the study, i.e.10 am = 600 minutes. The file details are as follows:

LBNP data: LBNP_level_times.mat. The data contains 1 structure (LBNPinf) of length 16 (corresponding to each subject) with the following fields

ts: time vector in minutes lbnp: LBNP value at each noted time Vital Sign data: raw_labchart_data.mat. The data contains 1 structure array (Labchart) of length 16 (corresponding to each subject) with the following fields

ts: time vector in minutes ecgs: ECG data MAP: MAP data pleth: pleth data recorded from a single channel (V) Sentec EIT data: raw_av_ST_impedance_data.mat. The data contains 1 structure array (STout) of length 16 (corresponding to each subject) with the following fields

t_thx: time vector in minutes corresponding to thorax data Z_thx: average impedance data at each time over the thorax t_spl: time vector in minutes corresponding to abdomen data Z_spl: average impedance data at each time over the abdomen Sciospec EIS data: raw_sciospec_dat.mat. The data contains 1 cell array & 1 structure array (sciodat) of length 16 (corresponding to each subject).

Cell array: Locations of the Sciospec measurements: 'Thoracic', 'Abdominal', 'Arm' Sciodat fields:

sciodat structure array of length 3 corresponding to the 'Thoracic', 'Abdominal', 'Arm' locations, respectively. Each component has the following fields

tvec: time vector in minutes fs: frequencies that the impedance is recorded over (Hz) Zmat: matrix of impedance data size time versus frequency erflg: not used Bioimpedance cardiography data: raw_cheetah_bioimpedance.mat. The data contains a cell array of column labels (col_labs, 1x11) and a matrix (cheetah_db) of the BC data.

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