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Paperdoi:10.1088/0967-3334/29/12/003

Preliminary evaluation of a new fibre-optic cerebral oximetry system

Venue listed2008Added Nov 5, 2026

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Authors: J P Phillips, R M Langford, P A Kyriacou, D P Jones

Physiological Measurement

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TL;DR

A new system for measuring the oxygen saturation of blood within tissue has been developed, for a variety of patient monitoring applications. A particular unmet need is in the central nervous system, and this project aims to devise a means for measuring blood oxygen saturation in the brain tissue of patients recovering from neurosurgery or head injury. Coupling light sources and a photodetector to optical fibres results in a probe small enough to pass through a cranial bolt of the type already in use for intra-cranial pressure monitoring.

  • Published in Physiological Measurement (2008).

Abstract

A new system for measuring the oxygen saturation of blood within tissue has been developed, for a variety of patient monitoring applications. A particular unmet need is in the central nervous system, and this project aims to devise a means for measuring blood oxygen saturation in the brain tissue of patients recovering from neurosurgery or head injury. Coupling light sources and a photodetector to optical fibres results in a probe small enough to pass through a cranial bolt of the type already in use for intra-cranial pressure monitoring. The development and evaluation of a two-wavelength fibre-optic reflectance photoplethysmography (PPG) system are described. It was found that good quality red and near-infrared PPG signals could be obtained from the finger using a fibre-optic probe. Experiments were conducted to find the inter-fibre spacings that yield signals most suitable for calculating oxygen saturation. Reliable signals could be obtained for inter-fibre spacings between 2 mm and 5 mm, the latter being the size of the maximum aperture in the cranial bolt. A preliminary measurement from human brain tissue is also presented.

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Tasks & signals

Signals

PPG

Keywords

Kyriacou BibliographyBrain Monitoring Icp

How it works

How Method works: Setup → Method → TargetSetup: Signals (PPG). Method: Method.SetupSignals: PPGSignalsPPGMethodMethod

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Phillips, J. P., Langford, R. M., Kyriacou, P. A., & Jones, D. P. (2008). Preliminary evaluation of a new fibre-optic cerebral oximetry system. Physiological Measurement. https://doi.org/10.1088/0967-3334/29/12/003
Phillips, J P, R M Langford, P A Kyriacou, and D P Jones. 2008. "Preliminary evaluation of a new fibre-optic cerebral oximetry system." Physiological Measurement. https://doi.org/10.1088/0967-3334/29/12/003.
Phillips, J. P., Langford, R. M., Kyriacou, P. A. and Jones, D. P. (2008) 'Preliminary evaluation of a new fibre-optic cerebral oximetry system', Physiological Measurement. doi: 10.1088/0967-3334/29/12/003.
Phillips, J P, et al. "Preliminary evaluation of a new fibre-optic cerebral oximetry system." Physiological Measurement, 2008. https://doi.org/10.1088/0967-3334/29/12/003.
J. P. Phillips, R. M. Langford, P. A. Kyriacou, and D. P. Jones, "Preliminary evaluation of a new fibre-optic cerebral oximetry system," Physiological Measurement, 2008, doi: 10.1088/0967-3334/29/12/003.
@article{phillips2008preliminary,
  title         = {{Preliminary evaluation of a new fibre-optic cerebral oximetry system}},
  author        = {Phillips, J. P. and Langford, R. M. and Kyriacou, P. A. and Jones, D. P.},
  year          = {2008},
  journal       = {Physiological Measurement},
  doi           = {10.1088/0967-3334/29/12/003}
}

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