Paperdoi:10.1088/1742-6596/85/1/012029
Photoplethysmographic measurements from central nervous system tissue
Journal of Physics: Conference Series
TL;DR
A new system for measuring the oxygen saturation of blood within tissue has been developed, for a number of potential patient monitoring applications. This proof of concept project aims to address the unmet need of real-time measurement of oxygen saturation in the central nervous system (CNS) for patients recovering from neurosurgery or trauma, by developing a fibre optic signal acquisition system for internal placement through small apertures. The development and testing of a two-wavelength optical fibre reflectance photoplethysmography (PPG) system is described together with measurements in rats and preliminary results from a clinical trial of the system in patients undergoing neurosurgery.
Abstract
A new system for measuring the oxygen saturation of blood within tissue has been developed, for a number of potential patient monitoring applications. This proof of concept project aims to address the unmet need of real-time measurement of oxygen saturation in the central nervous system (CNS) for patients recovering from neurosurgery or trauma, by developing a fibre optic signal acquisition system for internal placement through small apertures. The development and testing of a two-wavelength optical fibre reflectance photoplethysmography (PPG) system is described together with measurements in rats and preliminary results from a clinical trial of the system in patients undergoing neurosurgery. It was found that good quality red and near-infrared PPG signals could be consistently obtained from the rat spinal cord (n=6) and human cerebral cortex (n=4) using the fibre optic probe. These findings justify further development and clinical evaluation of this fibre optic system.
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Phillips, J. P., Kyriacou, P. A., Chang, S. H., Maney, K., George, K. J., & Langford, R. M. (2007). Photoplethysmographic measurements from central nervous system tissue. Journal of Physics: Conference Series. https://doi.org/10.1088/1742-6596/85/1/012029
Phillips, J P, P A Kyriacou, S H Chang, K Maney, K J George, and R M Langford. 2007. "Photoplethysmographic measurements from central nervous system tissue." Journal of Physics: Conference Series. https://doi.org/10.1088/1742-6596/85/1/012029.
Phillips, J. P., Kyriacou, P. A., Chang, S. H., Maney, K., George, K. J. and Langford, R. M. (2007) 'Photoplethysmographic measurements from central nervous system tissue', Journal of Physics: Conference Series. doi: 10.1088/1742-6596/85/1/012029.
Phillips, J P, et al. "Photoplethysmographic measurements from central nervous system tissue." Journal of Physics: Conference Series, 2007. https://doi.org/10.1088/1742-6596/85/1/012029.
J. P. Phillips, P. A. Kyriacou, S. H. Chang, K. Maney, K. J. George, and R. M. Langford, "Photoplethysmographic measurements from central nervous system tissue," Journal of Physics: Conference Series, 2007, doi: 10.1088/1742-6596/85/1/012029.
@inproceedings{phillips2007photoplethysmographic,
title = {{Photoplethysmographic measurements from central nervous system tissue}},
author = {Phillips, J. P. and Kyriacou, P. A. and Chang, S. H. and Maney, K. and George, K. J. and Langford, R. M.},
year = {2007},
booktitle = {Journal of Physics: Conference Series},
doi = {10.1088/1742-6596/85/1/012029}
}Added to the ChatPPG research hub
