Paperdoi:10.1109/embc.2019.8856437
Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
TL;DR
Differential Pathlength Factor (DPF) is a vital parameter for the Beer-Lambert law based calculations in estimating tissue perfusion using non-invasive optical techniques. A significant error in the measured concentration of oxyhemoglobin and deoxyhemoglobin has been reported due to the usage of wrong DPF values. The dependence of DPF on blood oxygen saturation and blood volume has never been studied earlier.
- Published in 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2019).
- DOI 10.1109/embc.2019.8856437.
Abstract
Differential Pathlength Factor (DPF) is a vital parameter for the Beer-Lambert law based calculations in estimating tissue perfusion using non-invasive optical techniques. A significant error in the measured concentration of oxyhemoglobin and deoxyhemoglobin has been reported due to the usage of wrong DPF values. The dependence of DPF on blood oxygen saturation and blood volume has never been studied earlier. In this work, a Monte Carlo model of perfused skin tissue was developed and executed at 660 nm and 940 nm optical wavelengths at a reflectance geometry. DPFs were simulated through 1-10 mm source detector separations at different blood volumes and oxygen saturations. Results showed higher DPFs at lower wavelengths and considerable variation with blood volume and oxygen saturation.
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Chatterjee, S., & Kyriacou, P. A. (2019). Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method. 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society. https://doi.org/10.1109/embc.2019.8856437
Chatterjee, Subhasri and Panayiotis A. Kyriacou. 2019. "Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method." 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society. https://doi.org/10.1109/embc.2019.8856437.
Chatterjee, S. and Kyriacou, P. A. (2019) 'Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method', 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society. doi: 10.1109/embc.2019.8856437.
Chatterjee, Subhasri, and Panayiotis A. Kyriacou "Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method." 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2019. https://doi.org/10.1109/embc.2019.8856437.
S. Chatterjee and P. A. Kyriacou, "Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method," 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2019, doi: 10.1109/embc.2019.8856437.
@inproceedings{chatterjee2019estimating,
title = {{Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method}},
author = {Chatterjee, Subhasri and Kyriacou, Panayiotis A.},
year = {2019},
booktitle = {2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
doi = {10.1109/embc.2019.8856437}
}Added to the ChatPPG research hub
