Paperdoi:10.1111/jsr.12725

2B-Alert App: A mobile application for real-time individualized prediction of alertness

Venue listed2018Added Nov 9, 2026

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Authors: Jaques Reifman, Sridhar Ramakrishnan, Jianbo Liu, Adam Kapela, Tracy J. Doty, Thomas J. Balkin, Kamal Kumar, Maxim Y. Khitrov

J Sleep Res 2019;28(2):e12725 (online 2018)

TL;DR

Smartphone app embedding a Bayesian learner in the UMP that adapts parameters to an individual after each PVT. Prospective 62-h total sleep deprivation study, n = 21, PVT every 3 h: app PVT RT profiles matched a reference PVT device; predictions for the last 24 h improved with more tests; after 12 PVTs accuracy was comparable to peak accuracy with all tests. During the 13 days before the lab phase participants logged sleep/caffeine in the app and wore a Philips Respironics Actiwatch-2 (full text via Europe PMC).

  • Form factor: software (sleep/schedule input; wrist actigraphy optional)

Abstract

Knowing how an individual responds to sleep deprivation is a requirement for developing personalized fatigue management strategies. Here we describe and validate the 2B‐Alert App, the first mobile application that progressively learns an individual’s trait‐like response to sleep deprivation in real time, to generate increasingly more accurate individualized predictions of alertness. We incorporated a Bayesian learning algorithm within the validated Unified Model of Performance to automatically and gradually adapt the model parameters to an individual after each psychomotor vigilance test. We implemented the resulting model and the psychomotor vigilance test as a smartphone application (2B‐Alert App), and prospectively validated its performance in a 62‐hr total sleep deprivation study in which 21 participants used the app to perform psychomotor vigilance tests every 3 hr and obtain real‐time individualized predictions after each test. The temporal profiles of reaction times on the app‐conducted psychomotor vigilance tests were well correlated with and as sensitive as those obtained with a previously characterized psychomotor vigilance test device. The app progressively learned each individual’s trait‐like response to sleep deprivation throughout the study, yielding increasingly more accurate predictions of alertness for the last 24 hr of total sleep deprivation as the number of psychomotor vigilance tests increased. After only 12 psychomotor vigilance tests, the accuracy of the model predictions was comparable to the peak accuracy obtained using all psychomotor vigilance tests. With the ability to make real‐time individualized predictions of the effects of sleep deprivation on future alertness, the 2B‐Alert App can be used to tailor personalized fatigue management strategies, facilitating self‐management of alertness and safety in operational and non‐operational settings.

Verbatim from the publisher's DOI record (opens in a new tab) · Publisher licence: http://creativecommons.org/licenses/by-nc-nd/4.0/

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Tasks & signals

Tasks

Stress

Signals

Keywords

FatigueBiomathematical Fatigue ModelUMP2b AlertPersonalisationPVT

How it works

How Method works: Setup → Method → TargetSetup: Signals (IMU); Form factor (software (sleep/schedule input; wrist actigraphy optional)). Method: Method. Target: Stress.SetupSignals: IMUxyzSignalsIMUForm factor: software (sleep/schedule input; wrist actigraphy optional)Form factorsoftware (sleep/schedule input; wrist…MethodMethodTargetStressStress

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Reifman, J., Ramakrishnan, S., Liu, J., Kapela, A., Doty, T. J., Balkin, T. J., Kumar, K., & Khitrov, M. Y. (2018). 2B-Alert App: A mobile application for real-time individualized prediction of alertness. J Sleep Res 2019, 28(2), e12725. https://doi.org/10.1111/jsr.12725
Reifman, Jaques, Sridhar Ramakrishnan, Jianbo Liu, Adam Kapela, Tracy J. Doty, Thomas J. Balkin, Kamal Kumar, and Maxim Y. Khitrov. 2018. "2B-Alert App: A mobile application for real-time individualized prediction of alertness." J Sleep Res 2019 28 (2): e12725. https://doi.org/10.1111/jsr.12725.
Reifman, J., Ramakrishnan, S., Liu, J., Kapela, A., Doty, T. J., Balkin, T. J., Kumar, K. and Khitrov, M. Y. (2018) '2B-Alert App: A mobile application for real-time individualized prediction of alertness', J Sleep Res 2019, 28(2), p. e12725. doi: 10.1111/jsr.12725.
Reifman, Jaques, et al. "2B-Alert App: A mobile application for real-time individualized prediction of alertness." J Sleep Res 2019, vol. 28, no. 2, 2018, p. e12725. https://doi.org/10.1111/jsr.12725.
J. Reifman et al., "2B-Alert App: A mobile application for real-time individualized prediction of alertness," J Sleep Res 2019, vol. 28, no. 2, p. e12725, 2018, doi: 10.1111/jsr.12725.
@article{reifman20182balert,
  title         = {{2B-Alert App: A mobile application for real-time individualized prediction of alertness}},
  author        = {Reifman, Jaques and Ramakrishnan, Sridhar and Liu, Jianbo and Kapela, Adam and Doty, Tracy J. and Balkin, Thomas J. and Kumar, Kamal and Khitrov, Maxim Y.},
  year          = {2018},
  journal       = {J Sleep Res 2019},
  volume        = {28},
  number        = {2},
  pages         = {e12725},
  doi           = {10.1111/jsr.12725}
}

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