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First page or project page of “Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction” (opens in a new tab)

Paperdoi:10.1109/embc.2014.6943998

Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction

Venue listed2014Added Nov 5, 2026

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Authors: K. Budidha, P. A. Kyriacou

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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First page or project page of “Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction” (opens in a new tab)

TL;DR

Pulse Transit Time (PTT) is the time it takes for an arterial pulsation to travel from the heart to a peripheral site. In recent times, PTT has been advocated as a marker for assessing increased vascular resistance. However, the reliability of PTT as a marker for cardiovascular risks and its inverse relation to beat-to-beat blood pressure is still being investigated.

  • Published in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2014).

Abstract

Pulse Transit Time (PTT) is the time it takes for an arterial pulsation to travel from the heart to a peripheral site. In recent times, PTT has been advocated as a marker for assessing increased vascular resistance. However, the reliability of PTT as a marker for cardiovascular risks and its inverse relation to beat-to-beat blood pressure is still being investigated. In order to validate the technique as a reliable marker of vascular resistance, PTT measurements were made using photoplethysmographic (PPG) signals obtained from multiple measurement sites in 12 healthy volunteers undergoing right hand immersion in ice water for 30 secs. PTT measurements were made from the ear canal (EC), the left (LIF) and right index fingers (RIF) using custom made photoplethysmographic probes. Activation of the sympathetic nervous system during the ice water immersion caused an increase in vascular resistance, which is associated with an increase in mean arterial pressure and a decrease in PTT in all measurement sites. However, the change in PTT was much larger in the RIF when compared to the LIF and the EC. This demonstrates the cerebral flow autoregulation and the profound peripheral vasoconstriction seen in the right hand. After the ice immersion period, the mean PTT measured from the EC returned to baseline, whereas the LIF PTT exceeded baseline values. This is due to the local vasodilation resulted from the activation of a thermoregulation mechanism.

Verbatim from Europe PMC (opens in a new tab) · Abstract via Europe PMC; © the authors/publisher

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Tasks & signals

Tasks

Blood pressure

Signals

PPG

Keywords

Kyriacou BibliographyBlood Pressure Vascular Health

How it works

How Method works: Setup → Method → TargetSetup: Signals (PPG). Method: Method. Target: Blood pressure.SetupSignals: PPGSignalsPPGMethodMethodTargetBlood pressureBlood pressure

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Budidha, K., & Kyriacou, P. A. (2014). Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. https://doi.org/10.1109/embc.2014.6943998
Budidha, K. and P. A. Kyriacou. 2014. "Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction." 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. https://doi.org/10.1109/embc.2014.6943998.
Budidha, K. and Kyriacou, P. A. (2014) 'Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction', 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. doi: 10.1109/embc.2014.6943998.
Budidha, K., and P. A. Kyriacou "Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction." 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014. https://doi.org/10.1109/embc.2014.6943998.
K. Budidha and P. A. Kyriacou, "Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction," 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014, doi: 10.1109/embc.2014.6943998.
@inproceedings{budidha2014investigation,
  title         = {{Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction}},
  author        = {Budidha, K. and Kyriacou, P. A.},
  year          = {2014},
  booktitle     = {2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
  doi           = {10.1109/embc.2014.6943998}
}

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