Paperdoi:10.3389/fnrgo.2023.1288922
Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy
Frontiers in Neuroergonomics 4:1288922, 2024
Arindam Biswas et al., "Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy", doi:10.3389/fnrgo.2023.1288922, CC BY 4.0
TL;DR
Integrated diffuse speckle contrast spectroscopy (iDSCS) measures deep-tissue blood flow with an ordinary photodiode and a custom integrating circuit rather than an expensive camera or single-photon detector. Tested on a human forearm against diffuse correlation spectroscopy, it was sensitive to deep blood flow while being low-cost, low-power and small enough for wireless wearable probes.
- Form factor: other
Abstract
Diffuse Correlation Spectroscopy (DCS) is a widely used non-invasive measurement technique to quantitatively measure deep tissue blood flow. Conventional implementations of DCS use expensive single photon counters as detecting elements and optical probes with bulky fiber optic cables. In recent years, newer approaches to blood flow measurement such as Diffuse Speckle Contrast Analysis (DSCA) and Speckle Contrast Optical Spectroscopy (SCOS), have adapted speckle contrast analysis methods to simplify deep tissue blood flow measurements using cameras and single photon counting avalanche detector arrays as detectors. Here, we introduce and demonstrate integrated Diffuse Speckle Contrast Spectroscopy (iDSCS), a novel optical sensor setup which leverages diffuse speckle contrast analysis for probe-level quantitative measurement of tissue blood flow. iDSCS uses a standard photodiode configured in photovoltaic mode to integrate photon intensity fluctuations over multiple integration durations using a custom electronic circuit, as opposed to the high frequency sampling of photon counts with DCS. We show that the iDSCS device is sensitive to deep-tissue blood flow measurements with experiments on a human forearm and compare the sensitivity and dynamic range of the device to a conventional DCS instrument. The iDSCS device features a low-cost, low-power, small form factor instrument design that will enable wireless probe-level measurements of deep tissue blood flow.
Verbatim from the publisher's DOI record (opens in a new tab) · Publisher licence: https://creativecommons.org/licenses/by/4.0/
Results on ChatPPG leaderboards
All leaderboardsNo results from this paper on ChatPPG leaderboards yet. Browse the leaderboards.
Tasks & signals
Signals
Keywords
How it works
- Wavelengths
- NIR laser (λ not in abstract)
Cite this paper
Biswas, A., Mohammad, P. P. S., Moka, S., Takshi, A. I., & Parthasarathy, A. B. (2024). Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy. Frontiers in Neuroergonomics , 2024, 4, 1288922. https://doi.org/10.3389/fnrgo.2023.1288922
Biswas, Arindam, Penaz Parveen Sultana Mohammad, Sadhu Moka, Arash I. Takshi, and Ashwin B. Parthasarathy. 2024. "Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy." Frontiers in Neuroergonomics , 2024 4: 1288922. https://doi.org/10.3389/fnrgo.2023.1288922.
Biswas, A., Mohammad, P. P. S., Moka, S., Takshi, A. I. and Parthasarathy, A. B. (2024) 'Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy', Frontiers in Neuroergonomics , 2024, 4, p. 1288922. doi: 10.3389/fnrgo.2023.1288922.
Biswas, Arindam, et al. "Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy." Frontiers in Neuroergonomics , 2024, vol. 4, 2024, p. 1288922. https://doi.org/10.3389/fnrgo.2023.1288922.
A. Biswas, P. P. S. Mohammad, S. Moka, A. I. Takshi, and A. B. Parthasarathy, "Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy," Frontiers in Neuroergonomics , 2024, vol. 4, p. 1288922, 2024, doi: 10.3389/fnrgo.2023.1288922.
@article{biswas2024noninvasive,
title = {{Non-invasive low-cost deep tissue blood flow measurement with integrated Diffuse Speckle Contrast Spectroscopy}},
author = {Biswas, Arindam and Mohammad, Penaz Parveen Sultana and Moka, Sadhu and Takshi, Arash I. and Parthasarathy, Ashwin B.},
year = {2024},
journal = {Frontiers in Neuroergonomics , 2024},
volume = {4},
pages = {1288922},
doi = {10.3389/fnrgo.2023.1288922}
}Added to the ChatPPG research hub