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Paperdoi:10.1088/1742-6596/238/1/012060

Optical measurement of blood flow changes in spinal cord injury

Venue listed2010Added Nov 5, 2026

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Authors: J P Phillips, P A Kyriacou, K J George, R M Langford

Journal of Physics: Conference Series

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TL;DR

Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fibreoptic photoplethysmography system was used to investigate whether pulsation of the small arteries in the spinal cord occurred before, during and after compressive loads were applied to the tissue.

  • DOI 10.1088/1742-6596/238/1/012060.

Abstract

Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fibreoptic photoplethysmography system was used to investigate whether pulsation of the small arteries in the spinal cord occurred before, during and after compressive loads were applied to the tissue. It was found that the signal amplitudes were reduced and this reduction persisted for at least five minutes after the compression ceased. It is hoped that results from this preliminary study may improve knowledge of the mechanism of spinal cord injury.

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Kyriacou BibliographyBrain Monitoring Icp

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Phillips, J. P., Kyriacou, P. A., George, K. J., & Langford, R. M. (2010). Optical measurement of blood flow changes in spinal cord injury. Journal of Physics: Conference Series. https://doi.org/10.1088/1742-6596/238/1/012060
Phillips, J P, P A Kyriacou, K J George, and R M Langford. 2010. "Optical measurement of blood flow changes in spinal cord injury." Journal of Physics: Conference Series. https://doi.org/10.1088/1742-6596/238/1/012060.
Phillips, J. P., Kyriacou, P. A., George, K. J. and Langford, R. M. (2010) 'Optical measurement of blood flow changes in spinal cord injury', Journal of Physics: Conference Series. doi: 10.1088/1742-6596/238/1/012060.
Phillips, J P, et al. "Optical measurement of blood flow changes in spinal cord injury." Journal of Physics: Conference Series, 2010. https://doi.org/10.1088/1742-6596/238/1/012060.
J. P. Phillips, P. A. Kyriacou, K. J. George, and R. M. Langford, "Optical measurement of blood flow changes in spinal cord injury," Journal of Physics: Conference Series, 2010, doi: 10.1088/1742-6596/238/1/012060.
@inproceedings{phillips2010optical,
  title         = {{Optical measurement of blood flow changes in spinal cord injury}},
  author        = {Phillips, J. P. and Kyriacou, P. A. and George, K. J. and Langford, R. M.},
  year          = {2010},
  booktitle     = {Journal of Physics: Conference Series},
  doi           = {10.1088/1742-6596/238/1/012060}
}

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